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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IREB2
All Species:
40
Human Site:
Y949
Identified Species:
62.86
UniProt:
P48200
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48200
NP_004127.1
963
105047
Y949
D
D
V
E
I
T
L
Y
K
H
G
G
L
L
N
Chimpanzee
Pan troglodytes
XP_523125
963
104993
Y949
D
D
V
E
I
T
L
Y
K
H
G
G
L
L
N
Rhesus Macaque
Macaca mulatta
XP_001107837
964
105069
Y950
D
D
V
E
I
T
L
Y
K
H
G
G
L
L
N
Dog
Lupus familis
XP_532364
964
105327
Y950
N
D
V
E
V
T
L
Y
R
H
G
G
L
L
N
Cat
Felis silvestris
Mouse
Mus musculus
Q811J3
963
104918
Y949
N
D
V
E
I
T
L
Y
K
H
G
G
L
L
N
Rat
Rattus norvegicus
Q62751
963
104783
Y949
N
D
V
E
I
T
L
Y
K
H
G
G
L
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513243
1011
110449
F997
N
D
V
E
I
T
L
F
K
H
G
G
I
L
N
Chicken
Gallus gallus
Q5ZLQ4
965
105344
Y951
N
D
V
E
I
T
L
Y
K
N
G
G
S
L
N
Frog
Xenopus laevis
Q6NTP2
955
104418
Y941
N
E
A
E
V
T
L
Y
K
H
G
G
I
L
S
Zebra Danio
Brachydanio rerio
XP_001341791
896
98752
F881
N
D
M
D
V
E
F
F
R
H
G
G
I
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524303
899
98560
Y884
T
E
V
D
I
T
Y
Y
K
N
G
G
I
L
N
Honey Bee
Apis mellifera
XP_392993
890
98796
F876
T
E
V
D
L
T
Y
F
K
H
G
G
I
L
N
Nematode Worm
Caenorhab. elegans
Q23500
887
96642
Y872
T
E
V
E
L
T
Y
Y
R
N
G
G
I
L
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42560
898
98134
F882
T
E
V
E
L
A
Y
F
D
H
G
G
I
L
Q
Baker's Yeast
Sacchar. cerevisiae
P19414
778
85350
Y765
E
Q
I
E
W
F
K
Y
G
S
A
L
N
K
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.1
92.5
N.A.
93.6
93.8
N.A.
84.4
82.1
68.5
62.9
N.A.
54.5
55.5
52.3
N.A.
Protein Similarity:
100
99.6
99.6
96.8
N.A.
96.6
97.1
N.A.
89.9
91.1
81
77
N.A.
72.4
71.8
67.5
N.A.
P-Site Identity:
100
100
100
80
N.A.
93.3
93.3
N.A.
80
80
60
33.3
N.A.
60
53.3
46.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
93.3
80
N.A.
86.6
86.6
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.1
26
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.5
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
7
0
0
0
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
60
0
20
0
0
0
0
7
0
0
0
0
0
0
% D
% Glu:
7
34
0
80
0
7
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
7
7
27
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
7
0
94
94
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
74
0
0
0
0
0
% H
% Ile:
0
0
7
0
54
0
0
0
0
0
0
0
47
0
7
% I
% Lys:
0
0
0
0
0
0
7
0
67
0
0
0
0
7
7
% K
% Leu:
0
0
0
0
20
0
60
0
0
0
0
7
40
94
0
% L
% Met:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
47
0
0
0
0
0
0
0
0
20
0
0
7
0
67
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
14
% Q
% Arg:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
7
0
0
7
0
7
% S
% Thr:
27
0
0
0
0
80
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
80
0
20
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
27
74
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _